姓名:孙成新
性别:男
职称/职务:副教授
学历:理学博士/博士后
电话:0851-28642516
传真:0851-28642335
电子邮件:suncx926@nenu.edu.cn; sunchengxin@zmu.edu.cn
通讯地址:遵义新蒲新区学府西路6号遵义医科大学,综合实验楼706室 / 学院2-603室
研究方向:
中药活性成分(多糖等)的提取纯化,及其在治疗肥胖、糖尿病、肿瘤和免疫疾病等疾病中的应用研究;
个人履历:
孙成新,男,中共党员,1985年5月生,博士,副教授。2008年7月毕业于东北师范大学生物科学专业,获得理学学士学位。2008年9月保送进入东北师范大学生命科学学院生物化学与分子生物学专业,攻读硕士和博士学位,2013年8月至2015年8月在University of Michigan, Ann Arbor(世界排名前50)联合培养学习。2016年1月-2018年7月在中山大学做博士后研究。2018年6月获得“吉林省优秀博士学位论文”。
社会兼职:
目前任贵州省药学会药学青年委员会秘书长,《遵义医科大学学报》青年编委,Frontiers in Drug Discovery Review Editor。
基金论文:
在Nature communications, Cell Reports等SCI收录期刊已发表论文20余篇,H-index 15,主持/结题国家自然科学基金、贵州省科技支撑课题、广东省自然科学基金、教育部博士后基金、企业委托横向课题等科研基金项目10项,近5年申请发明专利10余项,其中授权发明专利4项;
代表论文和专利:
1. Cheng, L. et al. Two New Bibenzyls from Dendrobium hercoglossum. Rec Nat Prod, doi:10.25135/rnp.291.2109.2198 (2021).
2. Cheng, L. et al. Dihydrophenanthrenes and phenanthrenes from Dendrobium terminale. Nat Prod Res, 1-8, doi:10.1080/14786419.2022.2048379 (2022).
3. Fang, Y. K., Liu, G. Y., Sun, C. X. & Xiao, S. J. A new triterpenoids from Nothotsuga longibracteata. J. Asian Nat. Prod. Res., 6, doi:10.1080/10286020.2020.1870960.
4. Lei, J. et al. Natural green deep eutectic solvents-based eco-friendly and efficient extraction of flavonoids from Selaginella moellendorffii: Process optimization, composition identification and biological activity. Sep Purif Technol 283, doi:ARTN 120203.10.1016/j.seppur.2021.120203 (2022).
5. Zhang, T. et al. Purification, chemical analysis and inhibitory effects on galectin-3 of enzymatic pH-modified citrus pectin. Food Chem X 12, 100169, doi:10.1016/j.fochx.2021.100169 (2021).
6. Sun, C., Jiang, L., Liu, Y., Shen, H., Weiss, S.J., Zhou, Y., Rui, L. Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Suppressing Adipose Triacylglycerol Lipase Expression 2016, Cell Reports, 17 (8), pp. 2015-2027.
7. Sun, C., Li, X., Liu, L., Canet, M.J., Guan, Y., Fan, Y., Zhou, Y Effect of fasting time on measuring mouse blood glucose level International Journal of Clinical and Experimental Medicine 2016, 9 (2), pp. 4186-4189.
8. Chen Z, Shen H, Sun C, Yin L, Tang F, Zheng P, Liu Y, Brink R and Rui L. Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity. American Journal of Physiology - Endocrinology and Metabolism 2015; 308: E460-E469.
9. Wang J, Sun C, Zheng Y, Pan H, Zhou Y and Fan Y. The effective mechanism of the polysaccharides from Panax ginseng on chronic fatigue syndrome. Archives of Pharmacal Research 2014; 37: 530-538.
10. Sun C, Chen Y, Li X, Tai G, Fan Y and Zhou Y. Anti-hyperglycemic and anti-oxidative activities of ginseng polysaccharides in STZ-induced diabetic mice. Food and Function 2014; 5: 845-848.
11. Chengxin Sun, Li X, Fan Y and Zhou Y. Pectic polysaccharides from Apocynum venetum L. promote proliferation of beta-cells. Glycoconjugate Journal 2013; 30:
12. Fan Y, Sun C, Gao X, Wang F, Li X, Kassim RM, Tai G and Zhou Y. Neuroprotective effects of ginseng pectin through the activation of ERK/MAPK and Akt survival signaling pathways. Molecular Medicine Reports 2012; 5: 1185-1190.
13. Du DY, Qin JS, Sun CX, Wang XL, Zhang SR, Shen P, Li SL, Su ZM and Lan YQ. Functional heterometallic coordination polymers with metalloligands as tunable luminescent crystalline materials. Journal of Materials Chemistry 2012; 22: 19673-19678.
14. Chengxin Sun,Yan Chen, Xinzhi Li, Guihua Tai, Yifa Zhou, Hypoglycemic activities of Ginseng pectin, 2012 National glycoconjugates Symposium
15. Han H, Chen Y, Bi H, Yu L, Sun C, Li S, Oumar SA and Zhou Y. In vivo antimalarial activity of ginseng extracts. Pharmaceutical Biology 2011; 49: 283-289.
16. Ni W, Zhang X, Bi H, Iteku J, Ji L, Sun C, Fang J, Tai G, Zhou Y and Zhao J. Preparation of a glucan from the roots of Rubus crataegifolius Bge. and its immunological activity. Carbohydrate Research 2009; 344: 2512-2518.
17. Preparation method of Apocynum acid polysaccharide membrane penetrating peptide oral insulin nanocomposite, ZL201710093564.8, invention patent, substantive examination, the first inventor
18. An enzyme method for extracting hypoglycemic ginseng polysaccharide and its application in food and medicine, ZL201410084031. X, China Patent
19. Application of Apocynum acid polysaccharide in diabetes medicine, ZL201310136288.0, China Patent
20. An acidic polysaccharide from Eucommia ulmoides, its extraction method and its application in the preparation of drugs for treating fatty liver, ZL2021111435327, China Patent
21. An acidic polysaccharide from Eucommia ulmoides, its extraction method and its application in the preparation of anti-colon cancer drugs, ZL2021111458282, China Patent